Currently Enrolling Clinical Trials

Trial Type	Qualifications	Location
Diabetic Kidney Disease Apply Now	Ages: 18-80 Have a clinical diagnosis of type 2 diabetes Have moderate to severe chronic kidney disease	Hamden Site Apply Now
Diabetic Retinopathy Apply Now	Ages: 18+ Have had a diagnosis of type 2 diabetes for at least 10 years Diagnosed with diabetic retinopathy Not currently receiving treatment for diabetic retinopathy HbA1c value of 7.0% to 10.0%, inclusive	Waterbury Site Apply Now
Diarrhea-Predominant Irritable Bowel Syndrome Apply Now	Ages: 18-65 Have diarrhea-predominant irritable bowel syndrome (IBS-D) Have had recurrent abdominal pain on average at least 1 day per week during the previous 3 months	Waterbury Site Apply Now
Gastroesophageal Reflux Disease (GERD) Apply Now	Ages: 18+ Have Diagnosis of Gastroesophageal Reflux Disease	Waterbury Site Apply Now
Heart Failure Apply Now	Ages: 18+ Have chronic heart failure or be at high risk for developing high potassium Have kidney disease	Waterbury Site Apply Now
Migraine Apply Now	Ages: 18-65 Diagnosis of Migraine for at least 1 year	Waterbury & Hamden Sites Apply Now
Obesity Apply Now	Ages: 18+ Do not have a diagnosis of Diabetes Have a body mass index (BMI) greater than or equal to 30 kg/m² - Individuals with a BMI between 27 and 30 may be eligible if they are diagnosed with certain qualifying conditions.	Waterbury Site Apply Now
Obesity/Cardiovascular Disease for non-diabetic overweight adults Apply Now	Ages: 45+ Have had a cardiovascular event (e.g. heart attack, stroke) Have a body mass index (BMI) greater than or equal to 27 kg/m²	Waterbury Site Apply Now
Osteoarthritis of the Knee Apply Now	Ages: 40-80 Diagnosis of osteoarthritis in the target knee (most painful knee) Primary source of pain throughout the body is due to osteoarthritis in the target knee Body mass index (BMI) less than or equal to 40 kg/m2	Waterbury Site Apply Now
Type 1 Diabetes Mellitus Apply Now	Ages: 18-75 Have a clinical diagnosis of Type 1 Diabetes Have an HbA1c value less than or equal to 10% Insulin dependent Not on an Insulin Pump	Hamden Site Apply Now
Type 1 Diabetes Mellitus With or without insulin pump Apply Now	Ages: 18-40 Have a clinical diagnosis of Type 1 Diabetes Insulin dependent	Hamden Site Apply Now
Type 2 Diabetes Mellitus for adults who have high Triglycerides Apply Now	Ages: 18+ Have Type 2 Diabetes Mellitus Have elevated Triglycerides or Cholesterol Have low HDL-C (low "good" cholesterol) Have an HbA1c value of 6.5% to 9.5%, inclusive	Waterbury Site & Hamden Site Apply Now
Type 2 Diabetes Mellitus for adults whose diabetes is only being treated with the medication Metformin Apply Now	Ages: 18+ Have Type 2 Diabetes Mellitus Have HbA1c levels between 7.0% - 10.0%, inclusive Are currently treated only with a stable dose of metformin	Waterbury Site Apply Now
Type 2 Diabetes Mellitus for adults whose diabetes is only being treated with the medication Metformin Apply Now	Ages: 18+ Have been diagnosed with type 2 diabetes mellitus Have an HbA1c value of 7.0% to 10.5%, inclusive Be on stable treatment with unchanged dose of metformin ≥ 1500 mg/day for at least 3 months	Hamden Site Apply Now